/* ══════════════════════════════════════════════════════════════
   SynthDNA Lab — Premium Dark Biotech Design System v2
   ══════════════════════════════════════════════════════════════ */
:root {
    --bg-primary: #0a0e17; --bg-secondary: #111827; --bg-card: #1a2234;
    --bg-card-hover: #1f2942; --bg-input: #0d1321;
    --border: rgba(255,255,255,0.06); --border-active: rgba(6,214,160,0.4);
    --text-primary: #e8ecf4; --text-secondary: #8b95a8; --text-muted: #5a6478;
    --accent-green: #06d6a0; --accent-blue: #118ab2; --accent-pink: #ef476f;
    --accent-yellow: #ffd166; --accent-purple: #8338ec;
    --gradient-primary: linear-gradient(135deg, #06d6a0, #118ab2);
    --font-sans: 'Inter', -apple-system, sans-serif;
    --font-mono: 'JetBrains Mono', monospace;
    --radius-sm: 8px; --radius-md: 12px; --radius-lg: 16px;
    --shadow-card: 0 4px 24px rgba(0,0,0,0.3);
    --tech-chemical: #06d6a0; --tech-enzymatic: #8338ec;
    --tech-photolitho: #ef476f; --tech-thermal: #ffd166;
}
*,*::before,*::after{margin:0;padding:0;box-sizing:border-box}
html{font-size:15px;scroll-behavior:smooth}
body{font-family:var(--font-sans);background:var(--bg-primary);color:var(--text-primary);min-height:100vh;overflow-x:hidden;-webkit-font-smoothing:antialiased}
#dna-bg{position:fixed;top:0;left:0;width:100vw;height:100vh;z-index:0;opacity:0.25;pointer-events:none}
.app-container{position:relative;z-index:1;max-width:1440px;margin:0 auto;padding:24px 32px 48px}
.app-header{display:flex;align-items:center;margin-bottom:28px;padding-bottom:20px;border-bottom:1px solid var(--border)}
.logo{display:flex;align-items:center;gap:16px}
.logo-icon{width:48px;height:48px;flex-shrink:0}
.logo-icon svg{width:100%;height:100%}
.logo h1{font-size:1.75rem;font-weight:800;background:var(--gradient-primary);-webkit-background-clip:text;-webkit-text-fill-color:transparent;background-clip:text}
.subtitle{font-size:0.8rem;color:var(--text-secondary);font-weight:400;margin-top:2px}
.main-grid{display:grid;grid-template-columns:440px 1fr;gap:24px;margin-bottom:24px}
.panel{background:var(--bg-card);border:1px solid var(--border);border-radius:var(--radius-lg);padding:24px;box-shadow:var(--shadow-card)}
.panel-header{display:flex;align-items:center;justify-content:space-between;margin-bottom:20px;flex-wrap:wrap;gap:12px}
.panel-header h2{font-size:1.1rem;font-weight:700}
.config-section{margin-bottom:18px}
.section-label{display:flex;align-items:center;gap:8px;font-size:0.75rem;font-weight:600;color:var(--text-secondary);text-transform:uppercase;letter-spacing:0.5px;margin-bottom:10px}
.value-badge{background:rgba(6,214,160,0.12);color:var(--accent-green);padding:2px 8px;border-radius:6px;font-size:0.72rem;font-weight:600;font-family:var(--font-mono)}

/* ── Tech Class Groups ── */
.tech-group{margin-bottom:12px}
.tech-group-label{font-size:0.65rem;font-weight:700;text-transform:uppercase;letter-spacing:0.8px;margin-bottom:6px;padding-left:4px;display:flex;align-items:center;gap:6px}
.tech-dot{width:8px;height:8px;border-radius:50%;display:inline-block}
.tech-group-cards{display:flex;gap:6px;flex-wrap:wrap}
.profile-card{flex:1;min-width:80px;padding:10px 10px;background:var(--bg-input);border:2px solid var(--border);border-radius:var(--radius-sm);cursor:pointer;transition:all 0.25s ease;text-align:center}
.profile-card:hover{border-color:rgba(255,255,255,0.15);background:var(--bg-card-hover);transform:translateY(-1px)}
.profile-card.active{box-shadow:0 0 16px rgba(6,214,160,0.15)}
.profile-card .card-name{font-size:0.7rem;font-weight:700;color:var(--text-primary);white-space:nowrap;overflow:hidden;text-overflow:ellipsis}
.profile-card .card-platform{font-size:0.58rem;color:var(--text-muted);line-height:1.3;margin-top:2px}
.profile-description{font-size:0.72rem;color:var(--text-secondary);line-height:1.6;margin-top:8px;padding:10px 12px;background:var(--bg-input);border-radius:var(--radius-sm);border-left:3px solid var(--accent-green);min-height:40px}

/* ── Sequencing Backend ── */
.seq-backend-row{display:flex;gap:8px}
.seq-btn{flex:1;padding:10px 8px;background:var(--bg-input);border:2px solid var(--border);border-radius:var(--radius-sm);cursor:pointer;transition:all 0.2s;text-align:center;color:var(--text-secondary);font-family:var(--font-sans);font-size:0.7rem;font-weight:600}
.seq-btn:hover{border-color:rgba(17,138,178,0.3)}
.seq-btn.active{border-color:var(--accent-blue);background:rgba(17,138,178,0.08);color:var(--accent-blue)}
.seq-backend-desc{font-size:0.68rem;color:var(--text-muted);margin-top:6px;padding:8px 10px;background:var(--bg-input);border-radius:var(--radius-sm);line-height:1.5}

/* ── Sliders ── */
.slider{-webkit-appearance:none;width:100%;height:6px;background:var(--bg-input);border-radius:3px;outline:none;border:1px solid var(--border)}
.slider::-webkit-slider-thumb{-webkit-appearance:none;width:20px;height:20px;border-radius:50%;background:var(--gradient-primary);cursor:pointer;box-shadow:0 2px 8px rgba(6,214,160,0.3)}
.slider-labels{display:flex;justify-content:space-between;font-size:0.65rem;color:var(--text-muted);margin-top:4px}
.size-grid{display:grid;grid-template-columns:repeat(4,1fr);gap:8px}
.size-btn{padding:10px;background:var(--bg-input);border:2px solid var(--border);border-radius:var(--radius-sm);color:var(--text-secondary);font-family:var(--font-mono);font-size:0.78rem;font-weight:600;cursor:pointer;transition:all 0.2s}
.size-btn:hover{border-color:rgba(6,214,160,0.3);color:var(--text-primary)}
.size-btn.active{border-color:var(--accent-green);background:rgba(6,214,160,0.08);color:var(--accent-green)}
.custom-size-wrapper{grid-column:1/-1;margin-top:4px}
.custom-size-input{width:100%;padding:10px 14px;background:var(--bg-input);border:1px solid var(--border);border-radius:var(--radius-sm);color:var(--text-primary);font-family:var(--font-mono);font-size:0.82rem;outline:none}
.custom-size-input:focus{border-color:var(--accent-green)}
.custom-size-input::placeholder{color:var(--text-muted)}
.dual-slider-row{display:flex;gap:12px}
.mini-input{flex:1;display:flex;align-items:center;gap:8px}
.mini-input span{font-size:0.72rem;color:var(--text-muted);min-width:28px}
.mini-input input{flex:1;padding:8px 10px;background:var(--bg-input);border:1px solid var(--border);border-radius:var(--radius-sm);color:var(--text-primary);font-family:var(--font-mono);font-size:0.82rem;outline:none;width:60px}
.mini-input input:focus{border-color:var(--accent-green)}
.format-row{display:flex;gap:8px}
.format-btn{flex:1;padding:10px;background:var(--bg-input);border:2px solid var(--border);border-radius:var(--radius-sm);color:var(--text-secondary);font-size:0.72rem;font-weight:600;cursor:pointer;transition:all 0.2s;font-family:var(--font-sans)}
.format-btn.active{border-color:var(--accent-purple);background:rgba(131,56,236,0.08);color:var(--accent-purple)}
.action-row{display:flex;gap:10px;margin-top:20px}
.btn{flex:1;padding:13px 14px;border:none;border-radius:var(--radius-md);font-family:var(--font-sans);font-size:0.82rem;font-weight:700;cursor:pointer;display:flex;align-items:center;justify-content:center;gap:8px;transition:all 0.25s;position:relative;overflow:hidden}
.btn-preview{background:var(--bg-input);color:var(--text-primary);border:1px solid var(--border)}
.btn-preview:hover{border-color:var(--accent-blue);box-shadow:0 0 16px rgba(17,138,178,0.15)}
.btn-generate{background:var(--gradient-primary);color:#0a0e17}
.btn-generate:hover{transform:translateY(-1px);box-shadow:0 6px 24px rgba(6,214,160,0.25)}
.btn:disabled{opacity:0.5;cursor:not-allowed;transform:none!important}
.btn-icon{font-size:1rem}

/* ── Tabs ── */
.tab-row{display:flex;gap:3px;background:var(--bg-input);border-radius:var(--radius-sm);padding:3px}
.tab{padding:6px 12px;border:none;background:transparent;color:var(--text-muted);font-family:var(--font-sans);font-size:0.7rem;font-weight:600;cursor:pointer;border-radius:6px;transition:all 0.2s}
.tab:hover{color:var(--text-secondary)}
.tab.active{background:var(--bg-card-hover);color:var(--text-primary)}
.tab-content{display:none;min-height:380px}
.tab-content.active{display:block;animation:fadeIn 0.3s ease}
@keyframes fadeIn{from{opacity:0;transform:translateY(6px)}to{opacity:1;transform:translateY(0)}}
.empty-state{display:flex;flex-direction:column;align-items:center;justify-content:center;min-height:300px;text-align:center;color:var(--text-muted)}
.empty-icon{font-size:2.5rem;margin-bottom:12px;opacity:0.5}
.empty-state p{max-width:280px;font-size:0.82rem;line-height:1.6}
.hidden{display:none!important}
.stats-row{display:grid;grid-template-columns:repeat(auto-fit,minmax(120px,1fr));gap:8px;margin-bottom:14px}
.stat-card{background:var(--bg-input);border:1px solid var(--border);border-radius:var(--radius-sm);padding:10px 12px}
.stat-card .stat-value{font-family:var(--font-mono);font-size:1.1rem;font-weight:700;color:var(--accent-green)}
.stat-card .stat-label{font-size:0.62rem;color:var(--text-muted);text-transform:uppercase;margin-top:2px}
.sequence-block{background:var(--bg-input);border:1px solid var(--border);border-radius:var(--radius-md);padding:12px 14px;margin-bottom:12px}
.seq-header{display:flex;justify-content:space-between;align-items:center;margin-bottom:6px}
.seq-label{font-size:0.62rem;font-weight:700;text-transform:uppercase;letter-spacing:0.5px;padding:3px 8px;border-radius:4px}
.center-label{background:rgba(6,214,160,0.12);color:var(--accent-green)}
.trace-label{background:rgba(239,71,111,0.12);color:var(--accent-pink)}
.seq-meta{font-size:0.65rem;color:var(--text-muted);font-family:var(--font-mono)}
.seq-display{font-family:var(--font-mono);font-size:0.7rem;line-height:1.7;color:var(--text-primary);word-break:break-all;white-space:pre-wrap;letter-spacing:1.2px;max-height:70px;overflow-y:auto}
.base-A{color:#06d6a0}.base-C{color:#118ab2}.base-G{color:#ffd166}.base-T{color:#ef476f}
.traces-container{max-height:320px;overflow-y:auto;padding-right:4px}
.traces-container::-webkit-scrollbar{width:4px}
.traces-container::-webkit-scrollbar-thumb{background:var(--border);border-radius:2px}

/* ── Profile Detail ── */
.profile-detail-grid{display:grid;grid-template-columns:1fr 1fr;gap:10px}
.detail-card{background:var(--bg-input);border:1px solid var(--border);border-radius:var(--radius-sm);padding:14px}
.detail-card h4{font-size:0.7rem;font-weight:700;color:var(--text-secondary);text-transform:uppercase;letter-spacing:0.3px;margin-bottom:8px}
.detail-row{display:flex;justify-content:space-between;align-items:center;padding:3px 0;border-bottom:1px solid rgba(255,255,255,0.03)}
.detail-row:last-child{border-bottom:none}
.detail-key{font-size:0.7rem;color:var(--text-muted)}
.detail-val{font-family:var(--font-mono);font-size:0.7rem;font-weight:600;color:var(--accent-green)}

/* ── Compare Tab ── */
.compare-controls{margin-bottom:16px}
.compare-select-row{display:flex;align-items:flex-end;gap:12px}
.compare-col{flex:1}
.compare-col label{display:block;font-size:0.68rem;font-weight:600;color:var(--text-muted);text-transform:uppercase;margin-bottom:6px}
.compare-col select{width:100%;padding:10px;background:var(--bg-input);border:1px solid var(--border);border-radius:var(--radius-sm);color:var(--text-primary);font-family:var(--font-sans);font-size:0.8rem;outline:none;cursor:pointer}
.compare-col select:focus{border-color:var(--accent-green)}
.compare-vs{font-size:0.9rem;font-weight:800;color:var(--text-muted);padding-bottom:10px}
.btn-compare-go{flex:0 0 auto;padding:10px 20px}
.compare-table{display:grid;grid-template-columns:1fr 1fr;gap:10px;margin-top:16px}
.compare-card{background:var(--bg-input);border:1px solid var(--border);border-radius:var(--radius-sm);padding:14px}
.compare-card h4{font-size:0.72rem;font-weight:700;margin-bottom:8px}

/* ── Progress / Gen ── */
.progress-wrapper{display:flex;align-items:center;gap:14px;margin-bottom:14px}
.progress-bar{flex:1;height:10px;background:var(--bg-input);border-radius:5px;overflow:hidden;border:1px solid var(--border)}
.progress-fill{height:100%;width:0%;background:var(--gradient-primary);border-radius:5px;transition:width 0.4s}
.progress-text{font-family:var(--font-mono);font-size:0.85rem;font-weight:700;color:var(--accent-green);min-width:42px;text-align:right}
.gen-message{font-size:0.8rem;color:var(--text-secondary);margin-bottom:16px;padding:10px 12px;background:var(--bg-input);border-radius:var(--radius-sm);font-family:var(--font-mono);border-left:3px solid var(--accent-blue)}
.gen-results{display:grid;grid-template-columns:1fr 1fr;gap:10px}
.result-card{background:var(--bg-input);border:1px solid var(--border);border-radius:var(--radius-sm);padding:12px}
.result-card .result-value{font-family:var(--font-mono);font-size:1rem;font-weight:700;color:var(--accent-green)}
.result-card .result-label{font-size:0.62rem;color:var(--text-muted);margin-top:2px}
.download-btn{grid-column:1/-1;padding:14px;background:var(--gradient-primary);color:#0a0e17;border:none;border-radius:var(--radius-md);font-family:var(--font-sans);font-size:0.9rem;font-weight:700;cursor:pointer;text-align:center;text-decoration:none;display:block;transition:all 0.2s}
.download-btn:hover{transform:translateY(-1px);box-shadow:0 6px 24px rgba(6,214,160,0.25)}

/* ── Viz ── */
.viz-grid{display:grid;grid-template-columns:repeat(3,1fr);gap:16px}
.viz-grid canvas{width:100%!important;height:220px!important;background:var(--bg-input);border:1px solid var(--border);border-radius:var(--radius-sm)}
#chart-compare-bars{width:100%!important;height:280px!important;background:var(--bg-input);border:1px solid var(--border);border-radius:var(--radius-sm)}

@media(max-width:1024px){.main-grid{grid-template-columns:1fr}.viz-grid{grid-template-columns:1fr}.app-container{padding:16px}}
.spinner{display:inline-block;width:16px;height:16px;border:2px solid rgba(6,214,160,0.3);border-top-color:var(--accent-green);border-radius:50%;animation:spin 0.8s linear infinite}
@keyframes spin{to{transform:rotate(360deg)}}